DNA methylation is a complicated
subject, but in essence it plays a crucial role in genetic expression - the way
information in genes is used by the human body to produce protein chains. We
all have a unique genetic code (also called the genome), registered in DNA,
which exists in every cell of our body, thus producing a
"fingerprint" of each of us. But other factors are factors that
influence how the genome is read (how easy it is to encode the protein chains
of other DNA components). One of these factors is methylation of DNA,
representing a form of epigenetics (epigenetics can be translated "above
genetics"). We should not be surprised that smoking has a major impact on
DNA and is thought to have an impact on the DNA methylation process as well. According
to http://organiceliquid.org, you
should know that some e juices retain their quality more than others, depending
on several factors, including the proportion of PG / VG, the type of flavor and
the nicotine concentration.
What is Methylation:-
To get a little bit into technical
details, methylation is the addition of a methyl group (CH3) to the DNA chain
at a specific point of one of the four DNA components, the cytosine.
Methylation is applied to the entire genome level, but specific distribution
helps us to relate to the risk of a particular condition. For example,
methylation at certain gene sequences leads to the suppression of "tumor
abolition" genes.
DNA Methylation in relation to smoking:-
Just as we look at the whole genome
as a whole to figure out how genetic variants help predict different diseases,
we can also look at specific genomic locations where DNA methylation differs
from individual to individual. Past studies have shown that there is a
consistent difference in the methylated DNA profiles in those who smoke. We
believe these differences were caused by smoking, although it is difficult to
confirm - the exact causes being very difficult to determine.
Perhaps you did not know, but
electronic cigarette maker manufacturers are not legally required to specify on
the bottle label the expiration date of the e liquid. However, almost all of
them do because it is a business practice whereby manufacturers guarantee that
the electronic cigarette fluid will have the same quality over the time period
mentioned. Just like the expiration date of the food, when it comes to e
liquids, many vapers can be impatient that it may become dangerous for the body
if it exceeds the time limit specified on the label. In this article I will
share some information about the expiration date of the electronic cigarette
liquids and what aspects to consider in determining whether an e liquid is safe
to digest or not. Look at this.
The expiration date of the e-liquid:-
Let's face it - we all have eaten or
drank something that had exceeded the expiration day or two, did we not? Well,
the expiration date is an information that remains at the manufacturer's
discretion to guarantee the quality of the product. Perhaps the more correct
term would be the "recommended term for consumption" because if a
product exceeded one day the expiration date does not mean it becomes dangerous
for the body, and often the quality is the same. It all depends on the
conditions in which the product was stored until it was consumed. The same
applies to electronic cigarette liquids. There is no universal expiration term
for e liquids, which is an arbitrary aspect, which refers more to taste, aroma
and consistency, and less to its potential negative effects on the body.
So how can you realize that the
liquid for the electronic cigarette has been "broken"? One of the
most obvious signs is the discoloration of the e liquid and the change in taste
and flavor, which become quite unpleasant. Fortunately, if you keep your e liquid
bottle in a heat-free and sun-free environment, you will have already consumed
it before it begins to lose its quality, no matter how small you are. Most
manufacturers offer a 2-year quality warranty. If you hold for more than 2
years, a bottle of electronic cigarette liquid means you're so seldom that
you'd better not do it.
Organic e juice, DNA Methylation and its effects
Reviewed by Pravesh Kumar Maurya
on
02:55
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